INTEGRA Biosciences AG

Cell Cultivation

INTEGRA provides innovative solutions for Cell Cultivation in laboratories. Efficient cell cultivation is driven by optimal supply of oxygen and nutrients, as well as by removing inhibiting metabolic waste products. These factors limit the maximum cell density obtainable from standard, homogeneous cell culture techniques which are consequently poor at achieving high expression levels of proteins. The two-compartment bioreactor CELLine is designed to overcome those limitations.

INTEGRA Biosciences AG
CELLine is a disposable cell cultivating bioreactor based on Two-Compartment Technology that boosts the production of monoclonal antibodies or recombinant proteins. Under optimal conditions, the cell concentration reached is about two magnitudes higher than the one obtained with conventional culture techniques. Thus, the concentration of expressed protein is typically 50 to 100 times higher than in standard cell culture disposables. CELLine is designed to maintain cells for several months in culture allowing to periodically harvest expressed proteins. More information

INTEGRA Biosciences AG
Adapter range: 1 to 8 channels (40 - 280 mm)
All waste collection bottles (up to 4 litres) are autoclavable.

VACUSAFE is a compact laboratory aspiration system providing a safe and efficient way to collect and contain biological liquid waste. Protecting the vacuum source from contamination by liquids and aerosols with an overflow trap and a filter is important when working with biological, chemical or radioactive liquids.

Common applications:
- Removal of media from cell cultures
- Removal of supernatants after centrifugation
- Removal of wash solutions from immunoassay well-plates More information