m2p-labs GmbH INTEGRA Biosciences AG Inoxpa

Laboratory Bioreactors / Fermentors

m2p-labs GmbH
The fully scalable BioLector® manages not only to run 48 cultivations in parallel, but also to perform real time online monitoring of the most common parameters (biomass, pH, DO and GFP). Furthermore, the system controls the temperature inside the cultivation chamber, the shaking speed as well as humidity. It operates with non-invasive, optical sensors and is due to the continuous and rigorous shaking ideally suited for aerobic and anaerobic cultures. In case that there is a high or very low oxygen level required, a CO2 enriched aeration, anaerobic conditions, or the possibility for measuring Fluorescence Resonance Energy Transfer (FRET), the system can be easily upgraded with additional modules.

The Biolector® Pro version extends the proven scalable BioLector® technology with an innovative microfluidic chip for extremely exact and slow dosing down to 50 nL. More information

m2p-labs GmbH
Pipetting volume range: 10 – 900 μL
Accuracy: ± 2%

This fully automated system combines a BioLector® with the precise and accurate liquid handling of a pipetting robot. The RoboLector® autonomously prepares media compositions from a full factorial design of experiments (DoE) and allows to add inducers and feed solutions during fermentation according to a pre-defined schedule or triggered by online process signals.

The RoboLector® L comes with a two-needle liquid-handling robot and 16 different deck positions on the worktable, whereas the more sophisticated RoboLector® XL provides 8-needles and 20 different deck positions. More information

INTEGRA Biosciences AG
CELLine is a disposable cell cultivating bioreactor based on Two-Compartment Technology that boosts the production of monoclonal antibodies or recombinant proteins. Under optimal conditions, the cell concentration reached is about two magnitudes higher than the one obtained with conventional culture techniques. Thus, the concentration of expressed protein is typically 50 to 100 times higher than in standard cell culture disposables. CELLine is designed to maintain cells for several months in culture allowing to periodically harvest expressed proteins. More information

INOXPA offers automated and customized CIP/SIP units to guarantee a controlled cleaning and sterilization of all elements required (tanks, pipes, pumps) in a reliable, repetitive and verifiable manner, without having to disassemble the entire process plants. The sterilization of the process plants is carried out with steam supplied by a clean steam generator. Chemical sterilization is also possible. Models include, manually operated, fully automated and mobile CIP units. The complete SIP as well as CIP circle is monitored by a PLC unit that controls every stage of the process. More information